ChatEUjordwalke: Built ChatGDPR on Replit. Finally, a safe way to use AI.

Codex anywhere and everywhere, all the time. Now your Mac doesn’t have to be unlocked for Codex to use your computer. From your phone, Codex can secu...

RT eugene: how it started how it’s going

RT Ivan Zhang: aight bro nvm the bouncer is an opp just show up whenever lol

📢Qwen3.7-Max just hit #3 on ITbench-AA — a fresh benchmark testing how well models handle real-world enterprise IT tasks, agentic-style. 🔧Agent...

RT John Burn-Murdoch: New from me: I had the pleasure of sitting in as host of BBC’s Radical podcast this week, and had a fascinating conversation wi...

RT Timothy Gowers @wtgowers: Another major problem, this time in additive combinatorics, has fallen, this time to humans rather than AI, but using met...

RT Crémieux: For the first year on record, wind and solar produced more electricity than coal in the U.S.

RT Noah Smith 🐇🇺🇸🇺🇦🇹🇼: The chuds were wrong about mRNA. It's magic.

RT Saloni: Guys, how do you invent a vaccine? Or wilder, how do you invent a vaccine during your PhD?! In a new episode of Hard Drugs, we talked to so...

RT Jelani Nelson: As I pointed out back in January: many UC Regents spoke in favor of keeping the SAT on May 21, 2020, only to unanimously vote to ban...

RT Ankit Gupta: my prompt for aspiring founders: assume the models reach superintelligence (arguably they have already), don't kill us all, and still ...

RT Brycent: YC is backing some absolute wizards!

RT Mayor Matt Mahan: UC STEM faculty are absolutely right, and this change is long overdue. We’re doing our kids a disservice and putting at risk the...

RT Pete Koomen: For more than a year we've been building tools at YC to make it easier to use agents at work. I enjoyed speaking publicly about this f...

RT Paul Graham: Gustaf (right) when he was in YC. You can see why our nickname for this startup was "the band".

RT Latent.Space: 🆕Biohub’s Protein World Model: ESMC-6B, ESMFold2, 6.8B proteins, 1.1B structures, antibody design, SAEs, & the bitter lesson for ...

OpenAI for self-improving tax agents:

GPT-5.5 is a uniquely good coding model

RT Kosta Derpanis (sabbatical in Zurich): .@ylecun making his usual impassioned case for LLMs and RL 🍒 for world models ... just kidding 🤓 Thank...

RT Occupy Democrats: BREAKING: Trump just got busted STEALING all the donation money from his “Board of Peace” fund to rebuild Gaza! This one REALLY...

RT Kenneth Roth: Trump is now "the most unpopular president since our poll started in 2009. His net approval rating is -24," due to his war of choice ...

RT Dr. Catharine Young: In case you still think there is any normalcy in how scientists are being treated at NIH. Photo credit: 27UNIHTED

RT Tymofiy Mylovanov: Petraeus: Putin is the personification of evil. He wants to reassemble as much of the former Soviet Union or Russian Empire as h...

RT biohub: A closer look at what we released today 🧵 ESMC is a language model trained on billions of protein sequences spanning the full diversity ...

RT Georgia Channing: today was a massive day for protein engineering. esmfold2 dropped—next gen of the esm series, fully open on @huggingscience. 1.1...

RT Eric Levitz: Trump could have presided over a very strong economy. All he had to do was...nothing: Inflation was trending downward, the AI boom was...

RT Zeming Lin: Get a state of the art protein structure prediction in just 9 lines of code. No MSAs needed.

RT Zeming Lin: Re ESMFold2 is a state of the art folding model. It's crazy good. The -Fast model does better on antibody-antigen complexes than AF3 wi...

RT nature: A newly released AI tool has generated an atlas of more than one billion predicted protein structures and billions more protein sequences. ...

RT Eric Topol: The ramp up of cancer immunotherapy is remarkable. Now we're seeing vaccines achieve some cures or remissions in the most refractory ca...

RT Don Winslow: Dear #MAGA and #Trump2024 Watch me take apart your cult leader and his lifetime of lies like a lego set in 4 minutes. Watch #DonaldTru...

RT Bilawal Sidhu: Gave google omni a sketched camera path and asked it to generate drone POV footage.

SpaceX has almost finished writing V1.0 of an in-house AI training stack in C that exact-maps to 220k GB300s with 800G NICs, making heavy use of pipel...

Grok Build improvements

RT Beff (e/acc): The rarest object type in the universe isn't black holes. It's us. Conscious matter. The flame of life. We have a duty to expand it i...

RT NASA Administrator Jared Isaacman: The entire event yesterday, launching missions, landers, rovers, tech demos building a Moon Base, and sci-fi cap...

RT Whole Mars Catalog: You haven't experienced real self-driving until you've tried Tesla Self-Driving 14.3.3 in Mad Max mode

RT Crémieux: For the first year on record, wind and solar produced more electricity than coal in the U.S.

"you can outsource your thinking, but you can’t outsource your understanding" easy to forget in todays AI era, worth remembering everyday as we all w...

Absolutely it isRexan Wong: NOW IS THE BEST TIME IN HISTORY TO START A COMPANYheres what the CEOs of @stripe + @Replit just said:> new business creation on stripe is up 2x YoY in march (even bigger spike than covid lockdowns)> 20% of startups charge their first customer within 30 days (was 8% in 2020)

Michele’s been applying AI on code since before LLMs existed, which is why frontier labs enjoy collaborating with our team. It’s been super fun work...

Replit supported more than 3,000 Saudi students to build their apps — many went on to become successful projects!

Use Runway in Replit

🔥🔥🔥Sergei: 4 years ago, I moved to New York to help start the Replit office in Brooklyn.Today, I walked by our billboards in front of Madison Square Garden. Proud!

RT Claude: Michele Catasta (@pirroh) is President and Head of AI @replit, the platform where anyone can build software in natural language. At 16, he ...

RT Aaron Horne: Try DemoGuards today. 14-day free trial, no CC required for trial. https://demoguards.com Created on @Replit, as well as the animation...

RT Usama Syed, MD: My wife (non-technical) built a fully functional iOS/Android app in 6 weeks... and it's made $1.5k on the app store since launch in...

http://x.com/i/article/2059629455602262016

New in the Claude Marketplace: @augmentcode, @boltdotnew, @coderabbitai, @hebbia, and @WeAreLegora. Apply your existing Anthropic spend commitment tow...

“The developer we’re building for has evolved.” @0xmts talks with @romainhuet about the new builder mindset, where ideas can move from thought to w...

RT Tibo: To simplify our Codex compute fleet management, we will be sunsetting GPT-5.2 and GPT-5.3-Codex in Codex on June 2nd when logged in with your...

⚙️ Behind the build of self-improving tax agents with Codex We co-built Tax AI with @ThriveHoldings around tax prep workflows so when reviewers fix ...

RT SkalskiP: RF-DETR is now available in @huggingface transformers state of the art in both detection and segmentation, outperforming YOLO architectur...

RT merve: RF-DETR just landed to @huggingface transformers 🥵🔥 sota real-time detection & segmentation models by @roboflow 💜 > play with our r...

RT Sayak Paul: Post-training in diffusion models is a very under-appreciated topic. So, we're delighted to try to change that at ECCV'26. Announcing a...

RT Sayak Paul: I am bullish and biased, but the best way way use flash attention 3 or 4 is via 🤗 kernels: ``` from kernels import get_kernel kernel...

"If you don't know who Cohere is, you will" - Prime Minister @MarkJCarney 🇨🇦

Use your SuperGrok or X Premium+ subscription in @kilocode. Try grok-build-0.1 for high speed and agentic coding intelligence, available in the Kilo I...

This marks the end of the M2 series, and MiniMax-M3 is coming

RT elie: new minimax sparse attention compared to deepseek v3.2 (DSA) and v4 (CSA) main changes: - based on GQA not MLA - block level selection like i...

Fast, faster, Qwen. 🚀 Thrilled to see Qwen3.5 reaching a record-breaking 580 tps for agentic workloads on the TokenSpeed engine! This milestone wou...

RT ClaudeDevs: We’ve shipped a security-guidance plugin for Claude Code that helps identify and fix vulnerabilities as you’re writing code. Availabl...

RT Anthropic: New on the Engineering Blog: The access and permissions we grant agents should evolve with their capabilities. In our own products, we s...

RT Quantus: The crypto industry is on a collision course with quantum computing. We just published a report on where it stands, what it does to crypto...

RT Dandalf: Trump is in a real bind now with Iran because he is correctly trying to tie the GCC under the Abraham accords as part of the Iran negotiat...

RT Eric Levitz: Trump could have presided over a very strong economy. All he had to do was...nothing: Inflation was trending downward, the AI boom was...

RT Y Combinator: Over the past year, we've been building our own internal agent infrastructure at YC: over 350 tools, self-improving skill loops, and ...

Gustaf (right) when he was in YC. You can see why our nickname for this startup was "the band".

One of my favorite pictures ever. 17 years ago.

RT Nicholas Kristof: There are multiple reasons why Sudan is the world's worst human crisis today, multiple bad actors. But the UAE is one of the wors...

RT Hiroo Onoda: god what a bleak chart

RT Eric Topol: The ramp up of cancer immunotherapy is remarkable. Now we're seeing vaccines achieve some cures or remissions in the most refractory ca...

It's time to make new software, not recreate old software When the form changes, what you create must change

Bring back the SAT at the UC system (yes that's correct, they don't even look at SATs anymore for college admissions there)

RT Liz4SF: Zero common sense, let’s do away with SATs bc it’s racist. UC regents should all be fired, along with/ racist admissions committees, wher...

RT AYi: 看完 Garry Tan 那篇关于 YC 的长帖， 大半夜的失眠了，想了好久。 心理学家 Alice Miller 一辈子在追一个问题， 为什么同样在恶劣家庭里长大， 有的孩...

Harm reduction has become harm acceleration Defund do-drugs-until-you-die policy and fund treatment and recovery

RT @johnloeber: There are several interesting things going on here. (1) The UCs were long known for their high standards, in particular UC…

Legalize standardized testing Legalize merit

If you abhor business and prosperity it will go elsewhere California and blue states need to stop voting by sound bite and start voting for prosperity...

RT Y Combinator: Over the past year, we've been building our own internal agent infrastructure at YC: over 350 tools, self-improving skill loops, and ...

RT Nick Mehta: Re @garrytan's quote below around using AI to create new products and services is so spot on - and so hard to do. 5 Failure Patterns in...

I get up in the morning to be a witness to greatness in YC founders.

http://x.com/i/article/2059649519722307584

RT Jitesh Ghanchi: I can't believe i'm using the same AI coding setup as the ceo of @ycombinator to build my products @garrytan's gstack is awesome. n...

RT Liam: $4 million and 18 months. Then $200 and 5 days. Same product, rebuilt by one man. That gap is the proof of what @garrytan just named: process...

RT Liam: http://x.com/i/article/2059578647653285888

RT Anish Acharya: the big thing that's changed since 2010 is you can be dramatically more ambitious in the type of software you build and charge drama...

RT Matt Lieberman: I signed it. The data are clear. Standardized tests are the best predictor of college success and the least biased indicator we hav...

RT otterboyinfrisco🏳️‍🌈: It really is not hyperbole to say that Peskin and SF's "progressives" really genuinely came up with the worst housing...

RT Bilawal Sidhu: Gave google omni a sketched camera path and asked it to generate drone POV footage.

Given the recent burst of activity around enterprise pricing and contracts, I think April 2026 was the month when both OpenAI and Anthropic found prod...

cognition is now the largest independent agent lab in the world. take the 200% utilization that everyone is hitting from this chart and run out the sa...

insanely good company to keep

Underappreciated how capable GPT-5.5 is at cybersecurity:

Codex for parallel browser-using subagents:

bring-your-own MCP servers:

Codex for transcribing and answering questions about a meeting in real time:

RT Roshan Rao: Announcing ESMFold2, our new state-of-the-art structure prediction model capable of predicting structure from single sequences or MSAs....

RT Randall Balestriero: It is refreshing to have some new arguments pointing at specific distributions (Gaussian) our embeddings must follow! Especial...

RT Alex Rives: Today we're announcing ESMFold2, an open scientific engine to power prediction, design, and discovery across protein biology. The new m...

RT David Klindt: Re Identifiability is what it means to learn the right latent space, the Gaussian is why LeJEPA works, and it's what makes planning t...

RT David Klindt: What does JEPA actually learn? We can finally prove it 🌍 So excited to share our theory of identifiable World Models: LeJEPA recov...

RT Daron Acemoglu: A post about Pope Leo XIV's encyclical on AI. Why the Pope is right, but perhaps not right enough. Artificial intelligence is resha...

RT Ed Elson: I read all 277 pages of SpaceX's IPO filing so you don't have to. Losses up 700%. Revenue decelerating. 107x price-to-sales multiple. It'...

RT Internet Archive: Musician and human rights activist Peter Gabriel sent a special congratulatory message to Brewster Kahle, founder and digital lib...

RT Tymofiy Mylovanov: The Telegraph: Macron tore up 65 years of doctrine to defend Europe with French nukes, with or without the US. Poland, Germany, ...

RT Yann LeCun: Re Major difference in my mind: - an engineer, given a problem, invents and tries multiple solutions and stops when the solution is goo...

Every millisecond matters. We’re open sourcing the tokenizer we built and deployed on production; that’s far efficient than huggingface and sentence...

RT Perplexity: We're open-sourcing the Unigram tokenizer we rebuilt to reduce CPU utilization by 5-6x. Small rerankers and embedders run in single-dig...

RT Pushmeet Kohli: When I was asked by the American Academy of Arts and Sciences to write an essay on my thoughts on how AI will accelerate Science, I...

RT X Freeze: I just found something interesting hidden on the SpaceX website Go to: http://SpaceX.com → Human Spaceflight → Space Station → scroll ...

RT Sawyer Merritt: NASA Administrator Jared Isaacman: "@SpaceX is probably our greatest commercial space company, hands down. We rely on SpaceX heavil...

RT Boris Skorobogaty: We spent a ton of time making worktrees actually work well for agent swarms and large repos. When you’re running 10s of agents ...

RT Jeff Bezos: Re @NASAMoonBase is the stepping stone towards everything that comes next.

RT WY: Been using Grok Build these past few days, and the thing that really got me hooked is Imagine and Imagine Video. I built a full dinosaur encycl...

RT Sean Parnell: .@elonmusk is a patriot who loves America, & @SpaceX has been a good-faith partner of the War Department.

RT NASA Administrator Jared Isaacman: The near impossible is becoming possible. We are building toward a sustained human presence at the lunar South P...

AI should dramatically increase quality of life and individual freedoms for people around the world. The OpenAI Foundation is making an initial $250M ...